This site is for the research, software and publications of Andrew Rambaut and members of his research group.

News

The BEAST software package has its own website: http://beast.bio.ed.ac.uk

We now have a site for posting analyses and news about emerging infectious diseases: http://epidemic.bio.ed.ac.uk/. This includes a new section on the novel human 2c genotype coronavirus.

 
A special issue of Phil. Trans. Roy. Soc. B on “Next Generation Molecular & Evolutionary Epidemiology of Infectious Disease” is now available: http://rstb.royalsocietypublishing.org/content/368/

 
Recent publications
MERS-CoV recombination: implications about the reservoir and potential for adaptation.
Dudas G & Rambaut A (2016) Virus Evolution 2, vev023.
Real-time, portable genome sequencing for Ebola surveillance.
Quick J, Loman NJ, Duraffour S, Simpson JT, Severi E, Cowley L, Bore JA, Koundouno R, Dudas G, Mikhail A, Ouédraogo N, Afrough B, Bah A, Baum JHJ, Becker-Ziaja B, Boettcher JP, Cabeza-Cabrerizo M, Camino-Sánchez Á, Carter LL, Doerrbecker J, Enkirch T, Dorival IG, Hetzelt N, Hinzmann J, Holm T, Kafetzopoulou LE, Koropogui M, Kosgey A, Kuisma E, Logue CH, Mazzarelli A, Meisel S, Mertens M, Michel J, Ngabo D, Nitzsche K, Pallasch E, Patrono LV, Portmann J, Repits JG, Rickett NY, Sachse A, Singethan K, Vitoriano I, Yemanaberhan RL, Zekeng EG, Racine T, Bello A, Sall AA, Faye O, Faye O, Magassouba NF, Williams CV, Amburgey V Winona L Davis E Gerlach J Washington F Monteil V Jourdain M Bererd M Camara A, Somlare H, Camara A, Gerard M, Bado G, Baillet B, Delaune D, Nebie KY, Diarra A, Savane Y, Pallawo RB, Gutierrez GJ, Milhano N, Roger I, Williams CJ, Yattara F, Lewandowski K, Taylor J, Rachwal P J., Turner D, Pollakis G, Hiscox JA, Matthews DA, Shea MKO, Johnston AM, Wilson D, Hutley E, Smit E, Di Caro A, Wölfel R, Stoecker K, Fleischmann E, Gabriel M, Weller SA, Koivogui L, Diallo B, Keïta S, Rambaut A, Formenty P, Günther S & Carroll MW (2016) Nature 530, 228-232.
Epidemic Reconstruction in a Phylogenetics Framework: Transmission Trees as Partitions of the Node Set .
Hall M, Woolhouse M & Rambaut A (2015) PLOS Comput Biol 11, e1004613.
Evolution and Spread of Ebola Virus in Liberia, 2014-2015.
Ladner JT, Wiley MR, Mate S, Dudas G, Prieto K, Lovett S, Nagle ER, Beitzel B, Gilbert ML, Fakoli L, Diclaro JW, Schoepp RJ, Fair J, Kuhn JH, Hensley LE, Park DJ, Sabeti PC, Rambaut A, Sanchez-Lockhart M, Bolay FK, Kugelman JR & Palacios, G (2015) Cell Host and Microbe 18, 659-669.
Ebola virus epidemiology, transmission, and evolution during seven months in Sierra Leone.
Park DJ, Dudas G, Wohl S, Goba A, Whitmer SL, Andersen KG, Sealfon RS, Ladner JT, Kugelman JR, Matranga CB, Winnicki SM, Qu J, Gire SK, Gladden-Young A, Jalloh S, Nosamiefan D, Yozwiak NL, Moses LM, Jiang PP, Lin AE, Schaffner SF, Bird B, Towner J, Mamoh M, Gbakie M, Kanneh L, Kargbo D, Massally JL, Kamara FK, Konuwa E, Sellu J, Jalloh AA, Mustapha I, Foday M, Yillah M, Erickson BR, Sealy T, Blau D, Paddock C, Brault A, Amman B, Basile J, Bearden S, Belser J, Bergeron E, Campbell S, Chakrabarti A, Dodd K, Flint M, Gibbons A, Goodman C, Klena J, McMullan L, Morgan L, Russell B, Salzer J, Sanchez A, Wang D, Jungreis I, Tomkins-Tinch C, Kislyuk A, Lin MF, Chapman S, MacInnis B, Matthews A, Bochicchio J, Hensley LE, Kuhn JH, Nusbaum C, Schieffelin JS, Birren BW, Forget M, Nichol ST, Palacios GF, Ndiaye D, Happi C, Gevao SM, Vandi MA, Kargbo B, Holmes EC, Bedford T, Gnirke A, Ströher U, Rambaut A, Garry RF & Sabeti PC (2015) Cell 161, 1516-1526.
Temporal and spatial analysis of the 2014-2015 Ebola virus outbreak in West Africa.
Carroll MW, Matthews DA, Hiscox JA, Elmore MJ, Pollakis G, Rambaut A, Hewson R, García-Dorival I, Bore JA, Koundouno R, Abdellati S, Afrough B, Aiyepada J, Akhilomen P, Asogun D, Atkinson B, Badusche M, Bah A, Bate S, Baumann J, Becker D, Becker-Ziaja B, Bocquin A, Borremans B, Bosworth A, Boettcher JP, Cannas A, Carletti F, Castilletti C, Clark S, Colavita F, Diederich S, Donatus A, Duraffour S, Ehichioya D, Ellerbrok H, Fernandez-Garcia MD, Fizet A, Fleischmann E, Gryseels S, Hermelink A, Hinzmann J, Hopf-Guevara U, Ighodalo Y, Jameson L, Kelterbaum A, Kis Z, Kloth S, Kohl C, Korva M, Kraus A, Kuisma E, Kurth A, Liedigk B, Logue CH, Lüdtke A, Maes P, McCowen J, Mély S, Mertens M, Meschi S, Meyer B, Michel J, Molkenthin P, Muñoz-Fontela C, Muth D, Newman EN, Ngabo D, Oestereich L, Okosun J, Olokor T, Omiunu R, Omomoh E, Pallasch E, Pályi B, Portmann J, Pottage T, Pratt C, Priesnitz S, Quartu S, Rappe J, Repits J, Richter M, Rudolf M, Sachse A, Schmidt KM, Schudt G, Strecker T, Thom R, Thomas S, Tobin E, Tolley H, Trautner J, Vermoesen T, Vitoriano I, Wagner M, Wolff S, Yue C, Capobianchi MR, Kretschmer B, Hall Y, Kenny JG, Rickett NY, Dudas G, Coltart CE, Kerber R, Steer D, Wright C, Senyah F, Keita S, Drury P, Diallo B, de Clerck H, Van Herp M, Sprecher A, Traore A, Diakite M, Konde MK, Koivogui L, Magassouba N, Av?i?-?upanc T, Nitsche A, Strasser M, Ippolito G, Becker S, Stoecker K, Gabriel M, Raoul H, Di Caro A, Wölfel R, Formenty P & Günther S (2015) Nature 524, 97-101.
Global circulation patterns of seasonal influenza viruses vary with antigenic drift.
Bedford T, Riley S, Barr I, Broor S, Chadha M, Cox N, Daniels R, Gunasekaran C, Hurt A, Kelso A, Klimov A, Lewis N, Li X, McCauley J, Odagiri T, Potdar V, Rambaut A, Shu Y, Skepner E, Smith D, Suchard MA, Tashiro M, Wang D, Xu X, Lemey P & Russell C (2015) Nature 523, 217-220.
The hidden history of HIV-1: establishment and early spread of the AIDS pandemic.
Faria NR, Rambaut A, Suchard MA, Baele G, Bedford T, Ward MJ, Tatem AJ, Sousa JD, Arinaminpathy N, Pépin J, Posada D, Peeters M, Pybus OG & Lemey P (2014) Science 346, 56-61.
Genomic surveillance elucidates Ebola virus origin and transmission during the 2014 outbreak.
Gire SK, Goba A, Andersen KG, Sealfon RSG, Park DJ, Kanneh L, Jalloh S, Momoh M, Fullah M, Dudas G, Wohl S, Moses LM, Yozwiak NL, Winnicki S, Matranga CB, Malboeuf CM, Qu J, Gladden AD, Schaffner SF, Yang X, Jiang P-P, Nekoui M, Colubri A, Coomber MR, Fonnie M, Moigboi A, Gbakie M, Kamara FK, Tucker V, Konuwa E, Saffa S, Sellu J, Jalloh AA, Kovoma A, Koninga J, Mustapha I, Kargbo K, Foday M, Yillah M, Kanneh F, Robert W, Massally JLB, Chapman SB, Bochicchio J, Murphy C, Nusbaum C, Young S, Birren BW, Grant DS, Scheiffelin JS, Lander ES, Happi C, Gevao SM, Gnirke A, Rambaut A, Garry RF, Khan SH & Sabeti PC. (2014) Science 345, 1369-1372.
Phylogenetic Analysis of Guinea 2014 EBOV Ebolavirus Outbreak.
Dudas G & Rambaut A (2014) PLoS Currents: Outbreaks 6

Latest software
2016-06-17 - BEAST
BEAST is a cross-platform program for Bayesian MCMC analysis of molecular sequences.
2016-04-01 - TempEst
Explore temporal signal and clocklikeness in trees (formerly Path-O-Gen)
2014-07-09 - FigTree
Produce high-quality figures of phylogenetic trees
2013-12-11 - Tracer
A program for analysing results from Bayesian MCMC programs such as BEAST & MrBayes
2011-10-28 - Seq-Gen
An application for the Monte Carlo simulation of DNA and amino acid sequence evolution along phyloge(...)
2008-11-29 - TreeStat
A program that calculates summary statistics of a set of trees
2002-12-01 - Phylogen
2002-10-04 - TreeEdit

 
Andrew Rambaut, 2007